Barbara Ketch once took on the role of Ghost Rider in an alternate reality in Marvel's What If series. Unlike her younger brother Danny Ketch, Barbara has a fierce and vengeful personality, fighting with the Spirit of Vengeance for control. Barbara wants to do more than inflict mere pain as punishment. She rejects the Spirit's guidelines and instead seeks to kill her targets. As Ghost Rider, Barbara begins a brutal mission for revenge, leaving a trail of dead bodies in her wake. Unfortunately, Barbara's story results in a tragic end.
Source:https://www.cbr.com/female-ghost-rider-marvel-what-if/