Throughout the Marvel Universe’s long history, many characters have come to regret their formative decisions. Jessica Jones actively cringes at the mere mention of her Jewel persona, while Tony Stark came to wince at the primitive nature of his Iron Man Armor Model 1. Arguably, no Marvel hero holds more regrets than Spider-Man. His entire identity as a hero is defined by the guilt that he feels toward failing to stop the burglar who would go on to murder his beloved Uncle Ben. Beyond this, the Wall-Crawler has suffered shattering death after death, resulting in the hero often becoming wracked with culpability and lament.
Source：https://www.cbr.com/one-of-spider-mans-biggest-regrets-has-nothing-to-do-with-uncle-ben/
