With the escape of the villainous Reed Richards better known as the Maker, the heroes of the Primary Marvel Universe knew it would only be a matter of time before they would have to deal with the threat he poses. As it turns out, they aren't the only iterations of Earth's Mightiest Heroes with that same concern, although no others who have stood in the Maker's way have lasted long. In fact, the Maker himself might very well be untouchable by anyone other than reality itself, which is exactly what has turned against him.
Source：https://www.cbr.com/ultimate-marvel-maker-time-war/
