The legendary shonen action anime Fullmetal Alchemist: Brotherhood often ranks near the very top among all great anime, such as on MyAnimeList.com, because of how much thought was put into every aspect of the story. Every major character in the Fullmetal Alchemist franchise embodies fascinating themes and has a cool design worthy of any top-rated shonen anime, including the villainous homunculi. Some anime villains are clearly designed just to give the heroes a good fight, but the homunculi of Fullmetal Alchemist: Brotherhood fame are entirely different.
Source:https://www.cbr.com/fullmetal-alchemist-homunculus-explained/