The Justice League face off against threats like no others. Over the years, the deadliest villains in the Multiverse have battled against the League. On many occasions, the heroes have stood between the Multiverse and annihilation at the hands of these monsters. The Justice League's foes have committed terrible atrocities throughout the Multiverse, but some of them have gone the extra mile when it comes to their villainous ways.
Source:https://www.cbr.com/justice-league-deadly-villains/