Over the course of their storied careers as antagonists in film and comics, the Predators, AKA the Yautja, have hunted some powerful foes. Most of them have been heavily armed and/or highly capable humans created for a Predator film or comic, but they have also stalked some famous faces like the Xenomorphs of the Alien film series and have had several comic crossovers that have pitted them against heroes from DC, Dark Horse Comics, and even Archie Comics. There's one famous face the Predator hasn't hunted yet, whose savage nature and signature set of claws make him a perfect and exciting target for the Yautja -- Wolverine.
Source:https://www.cbr.com/predator-vs-wolverine-benjamin-percy-interview/