As showcased to masterful effect in films like Spider-Man: Across the Spider-Verse, Spider-Man is a character that can transcend genre and setting. Completely different characters can be Spider-Man, so long as they commit to the same principles of heroism and responsibility codified by Stan Lee and Steve Ditko's original Spider-Man. But the latest version of Peter Parker -- fully introduced in Ultimate Spider-Man #1 by Jonathan Hickman, Marco Checchetto, Matthew Wilson, and VC's Cory Petit -- diverges in a quietly serious and potentially fascinating way.
Source:https://www.cbr.com/ultimate-spider-man-peter-parker-uncle-ben-changes-canon/