Lex Luthor hasn't played a huge role in Harley Quinn thus far, though thanks to actor Giancarlo Esposito and some sharp writing, he's invariably a scene-stealer. The series returns him to the 1970s Superfriends Saturday morning cartoon, where he memorably served as the head of the Legion of Doom. Harley Quinn reimagines him as a feckless CEO, overseeing hordes of supervillains enacting corporate-approved mayhem. It's made him one of the series' reliable straight men, with Poison Ivy, in particular, pointing out uncomfortable truths he'd rather sweep under the rug.
Source:https://www.cbr.com/harley-quinn-lex-luthor-superman-obsession/