In My Adventures with Superman Season 1, one of the most impressive aspects is how vulnerable Jack Quaid's Man of Steel is. Usually, Superman is depicted as almost invulnerable. The source material has led to many adaptations, including the Zack Snyder movies, using green kryptonite as his Achilles' Heel.
Source:https://www.cbr.com/my-adventures-with-superman-deadliest-suicide-squad/