Osamu Tezuka’s manga Dororo originally experienced a short, unlucky run on Weekly Shonen Sunday – canceled prematurely in 1968, the series still managed to live on, presumably thanks to the fame that its author reached by the end of his career. First adapted in 1969, the manga was picked up by MAPPA in 2019 for a 24-episode anime series that was mostly acclaimed as one of the best anime of the year – if not of the decade. Two years later, another film rose to success –with the critics, if perhaps not with the public – which had no apparent connection to Tezuka’s early work: Science SARU’s Inu-Oh.
Source:https://www.cbr.com/inu-oh-and-dororo-japanese-history-inspiration/