In Netflix’s The Fall of the House of Usher helmed by Mike Flanagan, the Usher family has made billions from their pharmaceutical company Fortunato. But just because they own a drug company doesn’t mean that they themselves can escape the ravages of disease. Head of the family Roderick Usher admits that he has been diagnosed with vascular dementia, specifically a rare form known by the acronym CADASIL. It turns out that this malady is generational, as it also afflicted Roderick’s mother, Eliza.
Source：https://www.cbr.com/fall-of-the-house-of-usher-cadasil-disease-explained/
