Some anime titles are experimental and blend seemingly disparate genres, like romantic comedy and spy drama. Other popular titles have fans diving into the story without blinking because the genres work so well together that it's as if they were meant to be written together. Most audiences love the basic genres, like historical fiction, science fiction, drama, fantasy, romance, and horror.
Source:https://www.cbr.com/10-new-anime-that-blend-genres-perfectly/