Considering the variety of heroes and villains who have inhabited the Marvel Universe over the course of more than sixty years, it is no surprise that many of them have come a long way from where they started. That being said, there are relatively few who were initially obscure bit players and have since gone on to become an indelible part of the world.
Source：https://www.cbr.com/x-men-mutant-typhoid-mary-spotlight-marvel/
