Fullmetal Alchemist: Brotherhood is a highly popular, well-respected shonen action anime series with a memorable combat system. Some characters in Fullmetal Alchemist are martial artists or sword users, but most others use the supernatural alchemy-based combat system one way or another. Trained alchemists can reshape matter at will, often with the hard sciences as a reference, and the deadly homunculi use alchemy-made Philosopher's Stones to power their superhuman abilities.
Source：https://www.cbr.com/strongest-fmab-characters-ranked/
