The Marvel Cinematic Universe introduced the famous comic book hero Spider-Man in Phase 3 in 2016. First appearing in Captain America: Civil War as a side character, Spider-Man has become a beloved part of the MCU with his trademark wit and humor, and most of all, his spider-themed combat abilities. Spidey has also taken part in many exciting battles in solo movies and Avengers features against a variety of enemies.
Source:https://www.cbr.com/spider-man-strongest-mcu-enemies/